HRs with 95% CIs comparing risk of death after adjusting for age in treated-versus-untreated cohorts
| Subgroup | HR (95% CI) |
|---|---|
| All subjects: treated-vs-untreated cohort | |
| Univariate | 1.62 (1.35–1.96) |
| Sex adjustment | 1.41 (1.17–1.71) |
| Sex + Charlson score adjustment | 1.17 (0.96–1.42) |
| Charlson index = 0 | |
| Univariate | 1.50 (0.86–2.61) |
| Sex adjustment | 1.46 (0.84–2.55) |
| Charlson index = 1–3 | |
| Univariate | 1.09 (0.83–1.43) |
| Sex adjustment | 1.00 (0.76–1.32) |
| Sex + Charlson score adjustment | 0.94 (0.71–1.24) |
| Charlson index >3 | |
| Univariate | 1.35 (0.99–1.83) |
| Sex adjustment | 1.26 (0.91–1.73) |
| Sex + Charlson score adjustment | 1.20 (0.87–1.66) |
| All subjects: treated vs symptomatic untreated cohort | |
| Univariate | 1.32 (1.08–1.62) |
| Sex adjustment | 1.20 (0.98–1.48) |
| Sex + Charlson score adjustment | 1.02 (0.82–1.25) |
| Charlson index = 0 | |
| Univariate | 1.22 (0.68–2.19) |
| Sex adjustment | 1.22 (0.68–2.19) |
| Charlson index = 1–3 | |
| Univariate | 0.97 (0.72–1.30) |
| Sex adjustment | 0.92 (0.68–1.24) |
| Sex + Charlson score adjustment | 0.86 (0.64–1.16) |
| Charlson index >3 | |
| Univariate | 1.07 (0.76–1.51) |
| Sex adjustment | 1.02 (0.72–1.45) |
| Sex + Charlson score adjustment | 1.00 (0.71–1.42) |