PPV and NPV for time-of-flight MR imaging as a screening test for complete obliteration for various disease-prevalence valuesa

Disease PrevalencePPVNPV
0.130.8%95.2%
0.250.0%89.8%
0.363.2%83.7%
0.472.7%76.7%
0.580.0%68.8%
0.685.7%59.5%
0.667b88.9%52.3%
0.790.3%48.5%
  • a Disease prevalence represents the pretest probability of complete obliteration without the time-of-flight MR imaging results. PPV represents the posttest probability of complete obliteration based on a screening test with 61.5% sensitivity and 84.6% specificity.

  • b Sample estimate by reader 1 was 67% (78/117) in Buis et al.1