Table 5:

Comparison of outcomes from clinical trials with the current study

Parameter	PROACT II	PROACT Placebo	IMS	Multi MERCI	Pivotal^{^a}	RMP Method	OAD Method
Median NIHSS score	17	17	18	19	17.6^{^b}	16	17
Minimum NIHSS score	≥4	≥4	≥10	≥8	≥8	≥4	≥4
Any recanalization	66%	18%	56%	68%	81.6%	52.5%	97.5%
Complete recanalization	19%	2%	11%	NA	27.2%	22.5%	66.7%
mRS <2	40%	25%	43%	36%	25%	41%	69.1%
90-day mortality	25%	27%	16%	34%	32.8%	28.2%	11.9%
SHT	10%	2%	6.3%	9.8%	11.2%	10.0%	4.44%

Note:—IMS indicates Interventional Management of Stroke; MERCI, Mechanical Embolus Removal in Cerebral Ischemia; PROACT, Prolyse in Acute Cerebral Thromboembolism; SHT, symptomatic hemorrhagic transformation.
↵a Penumbra Pivotal Stroke Trial.
↵b Mean.