Table 4:

Stratification of outcomes by methods of IA delivery of thrombolytics

VariableNo.RMP MethodOAD MethodP Value
No.4045
≥50% reperfusion8512 (30.0%)37 (82.2%)<.0001a
24-hour change in NIHSS (median)851.0 (−81.75–7)6.0 (1–10).0110b
NIHSS score change by hospital discharge853 (−8.25–8.0)9 (2–12).0064b
mRS ≤2 at 1–3 months81c16 (41.0%)29 (69.1%).0112b
Mortality at 3 months81c11 (28.2%)5 (11.9%).0656b
Infarct volume8565.6 (19.4–156)30.3 (6.60–55.5).0116b
Presence of hemorrhage8511 (27.5%)12 (26.7%).931a
Hemorrhage ≥25 mL855 (12.5%)4 (8.89%).589a
SHT854 (10.0%)2 (4.44%).318a
  • Note:—SHT indicates symptomatic hemorrhagic transformation.

  • a Pearson correlation.

  • b Wilcoxon rank sum test.

  • c Excludes patients who were known to have an mRS score >2 prior to ictus.