Frequency of typical MR imaging signs of histologically proved type 2 FCD reported in the literature
| Urbach et al, 20027 | Colombo et al, 200315 | Widdess-Walsh et al, 200514 | Besson et al, 200826 | Widjaja et al, 200828 | Kim et al, 20094 | Krsek et al, 20096 | Lerner et al, 20093 | This Study | |
|---|---|---|---|---|---|---|---|---|---|
| Period of study | 1996–2000 | 1996–2000 | 1990–2002 | NA | 1991–2005 | 1995–2005 | 2002–2005 | 2000–2007 | 2000–2011 |
| No. of patients | 22 | 15 | 48 | 26 | 13 | 28 | 16 | 64 | 71 |
| Negative findings on MRI | 0 | 5 (33%) | 10 (21%) | 0 | 2 (15%) | 6 (21%) | 0 | 1 | 29 (41%) |
| Cortical thickening | 18 (81%) | 10 (67%) | NA | NA | 8 (61%) | NA | 8 (50%) | 43 (67%) | 30 (71%) |
| Blurring of GWM junction | 8 (36%) | 13 (87%) | NA | NA | 11 (84%) | NA | 11 (69%) | 47 (73%) | 38 (90%) |
| Cortical signal changes | NA | 6 (40%) | NA | NA | 2 (15%) | NA | 10 (62%) | 22 (35%) | 21 (50%) |
| Subcortical signal changes | 22 (100%) | 13 (87%) | 27 (56%) | NA | 11 (84%) | NA | 14 (87%) | 64 (100%) | 42 (100%) |
| Transmantle sign | 18 (81%) | 3 (20%) | NA | 5 (19%) | 8 (72%) | NA | 6 (37%) | NA | 35 (83%) |
| Sulcal abnormalities | NA | NA | NA | NA | 3 (23%) | NA | 11 (69%) | NA | 22 (52%) |
| Atrophy | NA | 3 (20%) | NA | NA | 2 (15%) | NA | 7 (44%) | 11 (17%) | 0 |
Note:—NA indicates not available.