Demographic and clinical characteristics
| Variables | sd-aMCI | md-aMCI | sd-fMCI | sd-aMCI Compared with md-aMCI | sd-aMCI Compared with sd-fMCI | md-aMCI Compared with sd-fMCI |
|---|---|---|---|---|---|---|
| Age (years) | 65.8 ± 5.4 | 66.2 ± 5.2 | 67.0 ± 4.7 | .897 (NS) | .445 (NS) | .358 (NS) |
| Gender (F/M) | 7/11 | 22/13 | 8/5 | .100 (NS) | .220 (NS) | .933 (NS) |
| Education | 2.6 ± 0.6 | 1.9 ± 0.7 | 1.9 ± 0.8 | .019 (NS) | .120 (NS) | .284 (NS) |
| MMSE | 28.4 ± 1.5 | 27.7 ± 1.8 | 28.5 ± 1.5 | .115 (NS) | .884 (NS) | .141 (NS) |
| IADL | 8.8 ± 0.8 | 8.3 ± 0.8 | 7.8 ± 1.2 | .018 (NS) | .016 (NS) | .310 (NS) |
| HAD (anxiety) | 4.8 ± 3.3 | 6.1 ± 3.0 | 5.9 ± 3.0 | .147 (NS) | .176 (NS) | .726 (NS) |
| HAD (depression) | 1.9 ± 1.9 | 2.1 ± 1.7 | 2.9 ± 3.3 | .645 (NS) | .514 (NS) | .382 (NS) |
| Fazekas score | 0.7 ± 0.5 | 1.1 ± 0.9 | 1.2 ± 1.0 | .090 (NS) | .851 (NS) | .148 (NS) |
Note:—Data are presented as mean ± SD. Demographic and clinical characteristics did not differ between the 3 groups. NS refers to the Dunn Multiple comparison test adjusted P-value threshold for each demographic and clinical characteristic. sd-fMCI, n = 13; sd-aMCI, n = 18; md-aMCI, n = 35. HAD indicates Hospital Anxiety & Depression; IADL, Instrumental Activities of Daily Living; MMSE, Mini-Mental State Examination.