Pearson correlation coefficients (R2) for individual MRI biomarkers (top row) versus the LINCL score and biomarker combinations performed using PCAa
| ADC | WM FA | GM T2 | %CSF | NAA/Cr | PCA |
|---|---|---|---|---|---|
| 0.62 | 0.40 | 0.25 | 0.70 | 0.63 | |
| X | X | X | X | X | 0.70 |
| X | X | X | X | 0.75 | |
| X | X | X | 0.76 |
Note:—X indicates that this specific MRI biomarker was included in that combination of PCA analysis to produce the R2 quoted in the last column.
↵a Only the best 3 combinations are shown.