Inter-rater agreement of parameters not included in the scoring tool
| Parameter | κ | 95% CI |
|---|---|---|
| Inter-rater agreement <0.6 or lower limit of 95% CI, <.5 | ||
| Symmetric pattern | −0.04 | −0.08–0.01 |
| Ependymal enhancement | 0.38 | −0.15–0.91 |
| Fingerlike + projection | 0.46 | 0.10–0.82 |
| Proportion of discrete lesions | 0.39a | 0.24–0.54 |
| Not visualized on routine clinical brain imaging | ||
| Cervical spinal cord | 0.72 | 0.42–1.0 |
| Dot-dash sign | 0.71 | 0.46–0.97 |
| Cortical gray matter | 0.36 | 0.15–0.58 |
| Optic nerve lesion | 0.48 | −0.03–0.98 |
| Optic nerve enhancement | 0.82 | 0.50–1.0 |
| Optic nerve sheath enhancement | – | – |
| Extraoptic fat enhancement | – | – |
| Extraoptic muscle enhancement | – | – |
| Perineural enhancement | – | – |
| Not contributory to differentiating ADEM, MS, and SV-pACNS | ||
| Frontal lobar location | 0.60 | 0.36–0.85 |
| Temporal lobar location | 0.81 | 0.67–0.94 |
| Parietal lobar location | 0.80 | 0.66–0.94 |
| Occipital lobar location | 0.70 | 0.53–0.86 |
| ACA vascular territory | 0.56 | 0.37–0.75 |
| MCA vascular territory | 0.80 | 0.58–1.0 |
| PCA vascular territory | 0.64 | 0.47–0.82 |
| Vertebrobasilar vascular territory | 0.73 | 0.57–0.89 |
| Cerebellar peduncle | 0.76 | 0.59–0.93 |
| Target lesion | 0.78 | 0.62–0.94 |
| Nodular leptomeningeal enhancement | – | – |
| Linear leptomeningeal enhancement | – | – |
| Dural enhancement | – | – |
| Supratentorial lesion enhancement | 0.76 | 0.59–0.94 |
| Infratentorial lesion enhancement | 0.78 | 0.58–0.98 |
Note:—ACA indicates anterior cerebral artery; PCA, posterior cerebral artery; –, κ invalid due to low frequency of occurrence in ≥1 cell of the 2 × 2 table.
↵a Weighted κ reported.