Imaging characteristics of patients with primary tumor among those with HPV+ oropharynx cancer and matched patients with HPV− oropharynx cancer
Imaging Characteristic | HPV+ (n = 61) | HPV− (n = 61) | P Value | ||
---|---|---|---|---|---|
N | % | N | % | ||
Primary lesion is visible | .362 | ||||
Yes | 47 | 77.0 | 51 | 83.6 | |
No | 14 | 23.0 | 10 | 16.4 | |
Primary lesion is enhancing | .182 | ||||
Yes | 37 | 78.7 | 34 | 66.7 | |
No | 10 | 21.3 | 17 | 33.3 | |
Primary lesion demonstrates necrosis | 8 | 17.0 | 7 | 13.7 | .651 |
Yes | 39 | 83.0 | 44 | 86.3 | |
No | |||||
Primary lesion demonstrates well-defined border | .067 | ||||
Yes | 35 | 74.5 | 29 | 56.9 | |
No | 12 | 25.5 | 22 | 43.1 | |
Primary lesion is exophytic | .095 | ||||
Yes | 14 | 29.8 | 8 | 15.7 | |
No | 33 | 70.2 | 43 | 84.3 | |
Primary lesion demonstrates submucosal spread | .667 | ||||
Yes | 26 | 55.3 | 26 | 51.0 | |
No | 21 | 44.7 | 25 | 49.0 | |
Primary lesion invades adjacent muscle | .013 | ||||
Yes | 3 | 6.4 | 13 | 25.5 | |
No | 44 | 93.6 | 38 | 74.5 |