Table 2:

Comparison of clinical variables between preterm neonates with CHD with pWMLs and preterm neonates without CHD

CHD Preterm with pWMLs (n = 8)Control Preterm (n = 27)P Valuea
PCA, weeks, mean (SD)38.63 (3.36)42.61 (6.51).13a
GA, weeks, mean (SD)33.29 (1.89)30.67 (4.62).156a
PNA MRI, weeks, mean (SD)5.35 (4.38)11.095 (8.24).087a
PCA MRI, weeks, mean (SD)38.63 (3.36)42.61 (6.51).13a
Apgar 1 minute, median (n)6 (6)6 (21).860c
Apgar 5 minutes, median (n)8.5 (6)8 (21).878c
Apgar 10 minutes, median (n)6 (2)7 (3).747c
Size for GA338.216b
    Small, %6784
    Appropriate, %08
    Large, %625
ISAM, % (n)0 (5)8.3 (24).763d
Postnatal sepsis, % (n)42.9 (7)60.0 (25).706d
Hydrocortisone for BP, % (n)50 (6)18.5 (27).271d
Days on hydrocortisone, mean (SD)0.5 (0.55)1.741 (6.06).62a
Inotropes, % (n)100 (6)46.2 (26).02a
Days on dopamine, mean (SD)4.33 (4.23)3.81 (5.98).84a
  • Note:—PCA indicates postconceptional age; GA, gestational age; PNA, postnatal age; ISAM, infant of substance abusing mom; BP, blood pressure.

  • a ANOVA P values ≤.005.

  • b Measurements are average left and right.

  • c Mann-Whitney for testing difference in medians.

  • d χ2 for tests of homogeneity.