Imaging characteristics of nodal metastases among patients with HPV+ oropharynx cancer and matched patients with HPV− oropharyngeal cancer
| Imaging Characteristic | HPV+ (n = 59) | HPV− (n = 59) | P Value | ||
|---|---|---|---|---|---|
| N | % | N | % | ||
| Radiologic N stage | .754 | ||||
| N0 | 6 | 10.2 | 9 | 15.3 | |
| N1 | 7 | 11.9 | 8 | 13.6 | |
| N2 | 45 | 76.3 | 42 | 71.2 | |
| N3 | 1 | 1.6 | 0 | 0 | |
| Nodal metastases demonstrate extracapsular spread | .983 | ||||
| Yes | 16 | 30.2 | 15 | 30.0 | |
| No | 37 | 69.8 | 35 | 70.0 | |
| Nodal metastases demonstrate cystic morphology | .002 | ||||
| Yes | 19 | 35.8 | 5 | 10.0 | |
| No | 34 | 64.2 | 45 | 90.0 | |
| Nodal metastases demonstrate necrosis | .149 | ||||
| Yes | 37 | 69.8 | 41 | 82.0 | |
| No | 16 | 30.2 | 9 | 18.0 | |
| Nodal metastases demonstrate enhancement | .693 | ||||
| Yes | 33 | 62.2 | 33 | 66.0 | |
| No | 20 | 37.8 | 17 | 34.0 | |
| Nodal metastases include node of Rouvier | .474 | ||||
| Yes | 9 | 17.0 | 6 | 12.0 | |
| No | 44 | 83.0 | 44 | 88.0 | |