Volumetric comparison of radiotracers in MRI for GBM
| GBM (n=10) | TV (45.4 ± 26.5 cm3)a | CEV (21.6 ± 14.3 cm3)b |
|---|---|---|
| 62Cu-ATSM (8.2 ± 14.0 cm3) | P = .002 | P = .002 |
| FDG (11.0 ± 12.0 cm3) | P = .002 | P = .006 |
| MET (38.0 ± 19.0 cm3) | P = .56 | P = .06 |
Note:—The mean tumor volume (TV) and contrast-enhanced volume (CEV) were compared with the active volume of 62Cu-ATSM (T/B cutoff threshold ≥1.8), FDG (T/B cutoff threshold of ≥1.5), and MET (T/B cutoff threshold of ≥1.3). P values < .05 were considered to indicate statistical significance.
↵a TV was measured as a completely covered contrast-enhanced region with necrotic and cystic components.
↵b CEV was measured as a contrast-enhanced region without necrotic and cystic components on T1-weighted MRI with Gd-DTPA.