Summary table of DTI studies of the peritumoral region

Article	No.	Design	Measures	Tumor types	Criterion Standard	Conclusion^a
Deng et al, 2010²⁷	20	Prospective cohort study	FA, ADC	☒ Primary □ Metastasis □ Extra-axial	Tissue	Yes
Wang et al, 2009²⁸	49	Retrospective analysis	FA, p, q, L	☒ Primary □ Metastasis □ Extra-axial	None	Yes
Price et al, 2006²⁹	20	Prospective cohort study	FA, p, q	☒ Primary ☒ Metastasis □ Extra-axial	Tissue	Yes
Sinha et al, 2002¹³	9	Prospective cohort study	FA, MD	☒ Primary □ Metastasis □ Extra-axial	None	No
Provenzale et al, 2004²⁶	17	Retrospective analysis	FA, ADC	☒ Primary □ Metastasis ☒ Extra-axial	None	Yes
Lu et al, 2003²⁰	24	Prospective cohort study	FA, MD	☒ Primary ☒ Metastasis □ Extra-axial	None	Yes
Lu et al, 2004²⁴	40	Retrospective analysis	FA, MD, TII	☒ Primary ☒ Metastasis ☒ Extra-axial	None	Yes
Price et al, 2003²³	20	Prospective cohort study	RAI	☒ Primary ☒ Metastasis □ Extra-axial	None	Yes
Sundgren et al, 2006²¹	28	Prospective cohort study	FA, ADC	☒ Primary ☒ Metastasis □ Extra-axial	Follow-up	Yes
van Westen et al, 2006¹⁴	30	Prospective cohort study	FA, ADC	☒ Primary ☒ Metastasis ☒ Extra-axial	Tissue, cytology	No
Kinoshita et al, 2010³⁰	14	Retrospective analysis	FA, ADC, TII	☒ Primary ☒ Metastasis ☒ Extra-axial	None	No
Tropine et al, 2004²⁵	12	Prospective cohort study	FA, MD	☒ Primary □ Metastasis ☒ Extra-axial	None	Inconclusive

Note:—p indicates pure isotropic vector component; q, pure anisotropic vector component; L, total magnitude of the diffusion tensor; RAI, relative anisotropy index.
↵a Whether the study data suggest that DTI has utility in determining the extent of brain tumor infiltration.