Clinical studies testing penumbral imaging markers
| Study Name | Validation of the Imaging Biomarker | Testing a Treatment on the Basis of Selection of Patients with an Imaging Biomarker |
|---|---|---|
| DIAS,28 DEDAS,29 DIAS-2,30 IV tenecteplase,44,a | No | Yes |
| DEFUSE,31 DEFUSE-2,32,33 | Yes | No |
| EPITHET,34 MR-RESCUE35 | Yes | Yes |
↵a This trial required intracranial vessel occlusion on CTA and CTP mismatch for randomization.