Table 1:

Reproducibility of the in vitro quantification of brain phantom metabolites for the following: 1) fully encoded data, CS reconstruction of 2) prospective undersampled data, and 3) retrospective NUS data^{^a}

Metabolite Ratios	Phantom Conc./Cr	Fully Encoded (Mean ± SD)	Inc	Prospective Sampling (Mean ± SD)	Inc	Retrospective Sampling (Mean ± SD)	Inc
Cr391	1.000	0.811 ± 0.04	33	0.787 ± 0.06	33	0.813 ± 0.11	33
NAA	1.271	1.469 ± 0.05	33	1.532 ± 0.08	33	1.648 ± 0.15	33
PCh	0.086	0.126 ± 0.02	33	0.115 ± 0.01	33	0.109 ± 0.02	33
Cho	0.129	0.130 ± 0.01	33	0.135 ± 0.01	33	0.143 ± 0.02	33
GABA	0.100	0.101 ± 0.03	30	0.110 ± 0.02	12	0.136 ± 0.04	8
Glc	0.143	0.124 ± 0.05	3	0.174 ± 0.05	12	0.124 ± 0.02	6
Gln	0.357	0.205 ± 0.04	28	0.191 ± 0.04	32	0.203 ± 0.05	28
Glu	1.786	1.337 ± 0.11	33	1.304 ± 0.10	33	1.192 ± 0.12	33
GSH	0.286	0.143 ± 0.04	29	0.106 ± 0.03	31	0.109 ± 0.04	25
mIns	0.629	0.711 ± 0.10	33	0.688 ± 0.06	33	0.585 ± 0.06	33
NAAG	0.073	0.066 ± 0.03	25	0.044 ± 0.02	18	0.048 ± 0.01	14
PE	0.143	0.202 ± 0.06	14	0.157 ± 0.03	29	0.151 ± 0.04	14
Tau	0.257	0.173 ± 0.03	28	0.139 ± 0.03	15	0.136 ± 0.02	22
Thr	0.043	0.099 ± 0.03	8	0.168 ± 0.03	27	0.158 ± 0.05	23
tNAA	1.344	1.523 ± 0.06	33	1.555 ± 0.08	33	1.671 ± 0.15	33
tCho	0.214	0.256 ± 0.02	33	0.250 ± 0.02	33	0.252 ± 0.02	33
Glx	2.143	1.514 ± 0.13	33	1.495 ± 0.09	33	1.363 ± 0.11	33

Note:—Cr391 indicates N-methylene peak of Cr at 3.9 ppm; PCh, phosphocholine; GABA, γ-aminobutyrate; Gln, glutamine; GSH, glutathione; PE, phosphoethanolamine; Tau, taurine; SD, interscan standard deviation of the 33 spectra from 11 measurements; Conc., concentration; Inc, number of included spectra in the analysis; Glu, glutamate; Glc, glucose; NAAG, N-acetyl aspartylglutamate; Thr, threonine.
↵a Three central voxels have been chosen from each measurement. All the metabolite ratios have been calculated by normalizing with respect to Cr.