Table 1:

Outcome measures

OutcomeEntire Cohort (N = 202)SPAN-100-Positive (n = 15)SPAN-100-Negative (n = 181)
Median time from stroke onset to groin puncture (min) (range)238 (72–714)280 (140–450)235 (72–714)
Successful recanalization (after rescue therapy) as per core laba88% (171/194)93% (14/15)87% (151/173)
Median time from stroke onset to TICI 2b or 3 (or final DSA run) (min) (range)282 (100–800)322 (188–483)282 (100–800)
Stroke onset to successful revascularization categories
    0–4.5 hr46% (92/201)20% (3/15)47% (84/180)
    4.5–8 hr50% (101/201)73% (11/15)49% (89/180)
    ≥8 hr4% (8/201)7% (1/15)4% (7/180)
Device- or procedure-related serious adverse events7% (15/202)7% (1/15)8% (14/181)
Any intracranial hemorrhage19% (38/202)27% (4/15)19% (34/181)
Symptomatic intracranial hemorrhage1% (3/202)0% (0/15)2% (3/181)
90-Day clinical outcomes
    Death from any cause7% (14/202)27% (4/15)6% (10/181)
    Good functional recovery (modified Rankin Scale score 0–2)58% (117/202)27% (4/15)61% (110/181)
  • a Core laboratory missed the primary end point data of 8 subjects.