Demographic and baseline characteristics of all patients and by good collateral status, the locus of the thrombus, and 3-month outcome
| Characteristic | All Patients (n = 105) | Collateral Score 0–1 (n = 47) | Collateral Score 2–4 (n = 58) | P1 | mRS ≤2 at Day 90 (n = 54) | mRS 3–6 at Day 90 (n = 50) | P2 | Proximal Thrombus (ICA+M1P, n = 38) | Distal Thrombus (M1D+M2+M3, n = 67) | P3 |
|---|---|---|---|---|---|---|---|---|---|---|
| Age (yr) (mean) (SD) | 68.8 (13.5) | 70.1 (14.4) | 67.8 (12.7) | .38 | 66.4 (13.1) | 71.3 (13.6) | .06 | 66.0 (15.1) | 70.4 (12.3) | .11 |
| Male (%) | 60 (57) | 29 (62) | 31 (53) | .40 | 32 (59) | 28 (56) | .74 | 27 (71) | 33 (49) | .03 |
| NIHSS score before treatment (median) (IQR) | 13 (10) | 15 (7) | 11 (12) | .02 | 9 (10) | 17 (7) | <.001 | 18 (7) | 11 (10) | <.001 |
| NIHSS score 24 hours after thrombolysis (median) (IQR) | 6 (14) | 14 (14) | 3 (7) | <.001 | 2 (4) | 16 (11) | <.001 | 15 (10) | 3 (7) | <.001 |
| ASPECTS at admission CT (median) (IQR) | 10 (2) | 8 (3) | 10 (0) | <.001 | 10 (1) | 9 (2) | .20 | 9 (3) | 10 (2) | .07 |
| ASPECTS at 24 hours after CT (median) (IQR) | 7 (5) | 5 (4) | 8.5 (3) | <.001 | 9 (3) | 5 (4) | <.001 | 4 (5) | 8 (4) | <.001 |
| Collateral score (median) (IQR) | 2 (3) | 0 (1) | 3 (1) | <.001 | 3 (1) | 1 (2) | <.001 | 1 (3) | 2 (2) | .01 |
| Onset-to-treatment time (min) (mean) (SD) | 132 (27) | 124 (26) | 138 (27) | .008 | 133 (26) | 129 (29) | .46 | 131 (31) | 132 (25) | .85 |
| Hypertension (No.) (%) | 69 (65.7) | 31 (66) | 38 (66) | .96 | 36 (66.7) | 33 (66.0) | .94 | 22 (57.9) | 47 (70.1) | .20 |
| Diabetes (No.) (%) | 17 (16.2) | 9 (19) | 8 (14) | .46 | 6 (11.1) | 11 (22.0) | .13 | 8 (21.1) | 9 (13.4) | .31 |
| Atrial fibrillation (No.) (%) | 41 (39.0) | 19 (40) | 22 (38) | .79 | 23 (42.6) | 18 (36.0) | .49 | 12 (31.6) | 29 (43.3) | .24 |
| Coronary artery disease (No.) (%) | 35 (33.3) | 19 (40) | 16 (28) | .17 | 12 (22.2) | 23 (46.0) | .01 | 16 (42.1) | 19 (28.4) | .15 |
Note:—P1 indicates a P value between poor and good collateral status; P2, P value between mRS ≤ 2 and mRS > 2 groups; P3, P value between the proximal and distal thrombus groups; IQR, interquartile range; min, minutes.