Representative radiopharmaceuticals for amyloid imaging
| 11C-PiB | [11C]-2–4-(methylaminophenyl)- 6-hydroxybenzothiazole62 |
| 11C-BF227 | [11C]2-[2-(2-Dimethylaminothiazol-5-yl)ethenyl-6-[2-(fluoro)ethoxy]benzoxazole28 |
| 11C-AZD2184 | N-[11C]methyl)-2-(6-methylamino-pyridine-3-yl)-benzo[d]thiazole-6-ol66 |
| 18F-FDDNP | 2-(1-(6-[(2-[18F]fluoroethyl)(methyl)amino]-2-naphthyl)ethylidene)malononitrile67 |
| 18F-PiB | 2-[3-[18F]fluoro-4-(methylamino)phenyl]1,3-benzothiazole-6-ol68 |
| 18F-AV45 | (E)-4-(2-(6-(2-(2-(2-[18F]-fluoroethoxy)ethoxy)ethoxy)pyridin-3-yl)vinyl)-N-methyl benzenamine30 |
| 18F-BAY94–9172 | 4-(N-methylamino)-4′-(2-(2-(2-[18F]fluoroethoxy)-ethoxy)-ethoxy)-stilbene69 |
| 18F-AZD4694 | 2-(2-[18F]fluoro-6-(methylamino)pyridin-3-yl)benzofuran-5-ol30 |
Note:—18F-AV45 indicates florbetapir; 18F-BAY94–9172, florbetaben; 18F-PiB, flutemetamol.