Patient demographic data and summary of neuropsychological findings
| Patient | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 |
|---|---|---|---|---|---|---|---|---|---|---|
| Age (yr) (sex) | 52/M | 42/M | 39/M | 45/M | 54/M | 45/M | 69/M | 55/M | 39/M | 59/F |
| Ruptured/unruptured | R | R | R | R | R | R | U | R | R | U |
| CT gradea | 3 | 4 | 3 | 3 | 4 | 3 | NA | 4 | 4 | NA |
| Treatment | Trap | Clip | Clip 2nd | Clip | Clip | Clip | Clip | Clip | Clip | Clip |
| Months from treatmentb | 2 | 4 | 4b | 3 | 13 | 3 | 3 | 5 | 3 | 4 |
| MMSEc | 24 | 25 | 26 | 28 | 25 | 28 | 26 | 24 | 23 | 27 |
| IQd | 82 | 97 | 111 | 110 | 120 | 106 | 102 | 83 | 89 | 92 |
| MQe | 58 | 59 | 68 | 92 | 92 | 87 | 86 | 64 | 68 | 67 |
| IQ minus MQ | 24 | 38 | 43 | 18 | 28 | 19 | 16 | 19 | 21 | 25 |
| Attention/concentration | 81 | 80 | 114 | 138 | 131 | 115 | 115 | 91 | 94 | 133 |
| Delayed recall | <50 | <50 | <50 | <50 | 64 | 73 | 62 | <50 | <50 | <50 |
Note:—R indicates ruptured; U, unruptured; MMSE, Mini-Mental State Examination; IVH, intraventricular hemorrhage in the bilateral lateral ventricles; Trap, trapping; Clip, clipping; NA, not applied; WAIS-III, Wechsler Adult Intelligence Scale III; WMS-R, Wechsler Memory Scale-Revised.
↵a CT grade, proposed by Claassen et al,39 classifies the severity of aneurysmal subarachnoid hemorrhage on CT scans at onset into 5 grades from 0 to 4, according to the appearance of both of SAH and intraventricular hemorrhage in the bilateral lateral ventricles: grade 0, no SAH or IVH; grade 1, minimal SAH, no IVH; grade 2, minimal SAH, with IVH; grade 3, thick SAH, no IVH; grade 4, thick SAH, with IVH. In this scaling, the definition of “thick” is “completely filling” ≥1 cistern or fissure. In 2 patients with unruptured aneurysm (patients 7 and 10), grading was not applied.
↵b Months after second clipping.
↵c MMSE, used to assess cognitive impairment (full score 30).40
↵d IQ evaluated by the Wechsler Adult Intelligence Scale III.18
↵e MQ, general memory quotient, attention/concentration quotient, and delayed recall quotient, evaluated by Wechsler Memory Scale-Revised.19 Each quotient has a mean of 100 in the normal population and an SD of 15. A substantial difference between IQ (by the WAIS-III) and MQ (by the WMS-R) scores indicates that the person with amnesia has a particular impairment in memory—but not in the “intelligence” per se.20