Baseline characteristics of the study population (N = 200)
| Variables | No. |
|---|---|
| Median age (range) (yr) | 63 (35–92) |
| Female sex (%) | 63 (31.5) |
| Hypertension (%) | 131 (65.5) |
| Diabetes (%) | 60 (30) |
| Dyslipidemia (%) | 102 (51) |
| Smoker (%) | 57 (28.5) |
| Atrial fibrillation (%) | 73 (36.5) |
| Pre-tPA systolic BP (range) | 152 (110–215) |
| Pre-tPA NIHSS score (range) | 19 (3–33) |
| Median onset to treatment (range) | 155 (73–275) |
| TOAST criteria | |
| Large-artery atherosclerosis | 52 (26%) |
| Cardioembolic | 96 (48%) |
| Lacunar | 0 (0%) |
| Undetermined cause | 42 (21%) |
| Stroke of other etiology | 10 (5%) |
| Location of occlusion | |
| Tandem | 6 (3%) |
| Terminal ICA | 53 (26.5%) |
| M1 | 76 (38%) |
| Distal MCA | 65 (32.5%) |
| Modified Rankin Scale 0–1 at 3 mo (%) | 93 (46.6) |
| Modified Rankin Scale 5–6 at 3 mo (%) | 34 (17) |
Note:—TOAST indicates Trial of Org 10172 in Acute Stroke Treatment12; BP, blood pressure.