Differences of clinical and imaging thresholds in patients receiving thrombolysis versus untreated patients
| No Reperfusion Therapy | IV and/or IA Therapy | P Value | |
|---|---|---|---|
| DWI | |||
| AUC ± SE for predicting poor outcome | 0.935 ± 0.06 | 0.724 ± 0.05 | .011 |
| 90% Specificity for poor outcome (prognostic yield) (mL) | >19.7 (42.3%) | >51.8 (19.5%) | .016a |
| 95% Specificity for poor outcome (prognostic yield) (mL) | >20.5 (40.5%) | >74.8 (16.1%) | .007a |
| >30.6 (35.1%) | >103.1 (10.4%) | .003a | |
| NIHSS score | |||
| AUC ± SE for predicting poor outcome | 0.903 ± 0.06 | 0.827 ± 0.04 | .314 |
| 90% Specificity for poor outcome (prognostic yield) | >12 (37.8%) | >16 (23.0%) | .142a |
| 95% Specificity for poor outcome (prognostic yield) | >15 (27.0%) | >19 (14.9%) | .182a |
| 100% Specificity for poor outcome (prognostic yield) | >17 (16.2%) | >20 (9.2%) | .414a |
↵a P value for comparison among prognostic yields.