Survival analysis of MRI features for patients with solitary ISCMs (n = 39)
| Variable | Median Survival (daysa) (95% CI) | Hazard Ratio (95% CI) | P Valueb |
|---|---|---|---|
| No. of ISCMs | .022 | ||
| Solitary (n = 39) | 121 (42–187) | – | |
| Multiple (n = 10) | 53 (12–88) | – | |
| Noncord CNS/spinal metastases | .879 | ||
| No (n = 19) | 166 (87–334) | – | |
| Yes (n = 20) | 79 (26–184) | – | |
| Leptomeningeal metastases | .274 | ||
| No (n = 27) | 127 (38–231) | – | |
| Yes (n = 12) | 113 (24–790) | – | |
| Primary tumor/non-CNS metastases | .012 | ||
| No (n = 15) | 316 (38–790) | – | |
| Yes (n = 24) | 96 (32–166) | – | |
| Cord T2 hyperintensity ≥2 segmentsc | .037 | ||
| No (n = 10) | 184 (24–884) | – | |
| Yes (n = 28) | 111 (38–166) | – | |
| Cord T2 hyperintensity ≥3 segmentsc | .018 | ||
| No (n = 12) | 184 (24–790) | – | |
| Yes (n = 26) | 111 (38–166) | – | |
| Cord T2 hyperintensity (No. of segments)c (n = 38) | 121 (42–187) | 1.02 (0.96–1.09) | .541 |
| ISCM enhancement, superoinferior size (mm)c (n = 35) | 120 (42–187) | 1.01 (0.99–1.02) | .138 |
| ISCM enhancement, extent (No. of vertebral segments)c (n = 35) | 120 (42–187) | 1.08 (0.85–1.38) | .524 |
| Ratio, longitudinal extent of cord T2 hyperintensity to enhancementc (n = 34) | 119 (40–187) | 1.03 (0.94–1.13) | .477 |
| Rim signc | .621 | ||
| No (n = 18) | 79 (26–643) | – | |
| Yes (n = 17) | 127 (40–299) | – | |
| Flame signc | .068 | ||
| No (n = 19) | 127 (42–734) | – | |
| Yes (n = 16) | 96 (26–299) | – | |
| Rim/flame signsc | .143 | ||
| Neither (n = 13) | 121 (32–884) | – | |
| Rim sign only (n = 6) | 147 (21–790) | – | |
| Flame sign only (n = 5) | 26 (15–643) | – | |
| Both signs (n = 11) | 120 (38–316) | – |