Baseline characteristics, imaging, and clinical outcomes (N = 207)a
| Characteristics | Collateral-Flow Grade | P Value | |
|---|---|---|---|
| 0–1 (n = 76) | 2–4 (n = 131) | ||
| Age (yr) | 69 (62–76) | 67 (58–73) | .105 |
| Male | 50 (65.8%) | 75 (57.3%) | .226 |
| Baseline NIHSS | 17 (13–21) | 16 (12–19) | .041 |
| Baseline ASPECTSDWIb | 7 (5–8) | 8 (6–9) | .004c |
| SBP (mm Hg) | 148 (131–176) | 146 (126–168) | .520 |
| DBP (mm Hg) | 82 (72–90) | 82 (71–97) | .470 |
| Blood glucose level (mg/dL) | 126 (117–156) | 126 (111–159) | .861 |
| Occlusion site | .000 | ||
| ICA-T or ICA-L | 38 (50.0%) | 22 (16.8%) | |
| MCA M1 | 26 (34.2%) | 103 (78.6%) | |
| ICA/M1 tandem | 12 (15.8%) | 6 (4.6%) | |
| IV rtPA | 41 (53.9%) | 62 (47.3%) | .359 |
| Onset-to-puncture (min) | 220 (160–290) | 245 (175–325) | .055 |
| Puncture-to-reperfusion (min) | 77 (54–104) | 66 (44–90) | .053 |
| Onset-to-reperfusion (min) | 297 (224–383) | 307 (244–395) | .342 |
| 3-Month favorable outcome | 35 (46.1%) | 82 (62.6%) | .021 |
| Procedure-related complications | 4 (5.3%) | 8 (6.1%) | 1.000c |
| Symptomatic ICH | 4 (5.3%) | 6 (4.6%) | 1.000c |
| Ischemic brain edema | 7 (9.2%) | 8 (6.1%) | .406 |
| Mortality | 11 (14.5%) | 13 (9.9%) | .324 |
Note:—SBP indicates systolic blood pressure; DBP, diastolic blood pressure; ICH, intracranial hemorrhage.
↵a Numbers in parentheses are median (interquartile range) or number (%).
↵b Two hundred one DWI images at baseline (72 in 0–1 and 129 in 2–4; 97.1% in total) were available for ASPECTSDWI analysis.
↵c Fisher exact test for categoric variables/Mann-Whitney U test for continuous variables.