Analysis of clinical symptoms and outcomes of suprasellar papillary craniopharyngioma and suprasellar germ cell tumors
| Variables | PCP (n = 18) | GCT (n = 17) | OR | 95% CI | P Valuea |
|---|---|---|---|---|---|
| Age (yr) | 46 ± 13.9 (21–70) | 23 ± 7.1 (16–43) | <.0001 | ||
| Sex (male:female) | 13:5 | 13:4 | 1.3 | .27–5.7 | .7738 |
| Symptoms | |||||
| Visual field deficits | 12 (67%) | 6 (35%) | .27 | .07–1.1 | .0634 |
| Hypopituitarismb | 12 (71%) | 12 (75%) | 1.3 | .27–5.8 | .7761 |
| Hyperprolactinemiac | 14 (93%) | 11 (67%) | .16 | .02–1.5 | .0834 |
| Hypothalamic dysfunction, including diabetes insipidus | 2 (11%) | 11 (65%) | 15 | 2.5–87 | .0010 |
| Initial management | .0303 | ||||
| Total resection | 7 (39%) | 3 (18%) | 1.0 | – | |
| Subtotal resection | 6 (33%) | 1 (6%) | .39 | .03–4.8 | |
| Partial resection or biopsy | 3 (17%) | 6 (35%) | 4.7 | .67–32 | |
| Radiation or radiosurgery | 2 (11%) | 7 (41%) | 8.2 | 1.03–65 | |
| Outcome | |||||
| Recurrenced | 13 (81%) | 4 (24%) | .10 | .02–.50 | .0031 |
| Survival (mean) | 39.6 ± 32.02 (2–118) | 52.4 ± 40.32 (13–123) | .3815 |