Characteristic | Summarya |
---|---|
Demographics | |
Female sex | 41/75 (55%) |
Age at enrollment (yr) (n = 75) | 36.6 ± 19.9 |
Age at brain malformation diagnosis (yr) (n = 68) | 30.1 ± 19.7 |
HHT-related symptoms | |
Epistaxis | 66/73 (90%) |
Anemia | 20/72 (28%) |
GI bleeding | 5/67 (7%) |
Pulmonary AVM | 45/69 (65%) |
Liver VM | 4/66 (6%) |
HHT-causing mutation | |
ALK1 | 13/45 (29%) |
Endoglin | 27/45 (60%) |
SMAD4 | 1/45 (2%) |
All test findings negative | 4/45 (9%) |
Note:—GI indicates gastrointestinal; VM, vascular malformations.
↵a Summary is the No. of observations with specified value over the total No. (and the percentage) or the mean ± SD.