Table 1:

Average percentage of change in total tissue volume estimation between original and masked images^{^a}

Method	H1			H2			H3
Method	GM	WM	CSF	GM	WM	CSF	GM	WM	CSF
ANN	0.33 ± 0.42	−0.23 ± 0.28	0.11 ± 0.11	1.59 ± 1.37	−0.56 ± 0.46	0.78 ± 0.76	0.25 ± 0.31	−0.16 ± 0.28	−0.09 ± 0.09
FCM	0.28 ± 0.37	−0.22 ± 0.29	0.09 ± 0.11	2.28 ± 2.26	−0.90 ± 0.83	0.94 ± 0.90	0.28 ± 0.23	−0.25 ± 0.20	0.08 ± 0.09
FANTASM	0.23 ± 0.26	−0.18 ± 0.21	0.08 ± 0.08	1.34 ± 1.13	−0.49 ± 0.37	0.80 ± 0.73	0.26 ± 0.22	−0.24 ± 0.19	0.07 ± 0.08
FAST	0.29 ± 0.36	−0.29 ± 0.36	0.12 ± 0.13	1.92 ± 1.59	−1.28 ± 1.03	0.47 ± 0.39	0.34 ± 0.28	−0.37 ± 0.31	0.12 ± 0.17
SPM5	0.20 ± 0.30	−0.21 ± 0.20	−0.14 ± 0.54	0.10 ± 2.68	−1.04 ± 3.01	0.53 ± 0.51	0.04 ± 0.17	−0.18 ± 0.36	0.15 ± 0.23
SPM8	0.08 ± 0.09	−0.08 ± 0.08	−0.04 ± 0.18	0.55 ± 0.34	−0.93 ± 0.55	0.54 ± 0.42	0.09 ± 0.15	−0.23 ± 0.25	0.17 ± 0.23

↵a The results are divided by tissue and hospital. Reported values are the means ± SD. Positive values indicate a tissue overestimation on original images compared with masked.