Table 2:

The P values in the last column show results the from paired t test analysis on log(Ktrans) in pig brains estimated from DCE-MRa

Animal Ear Tag−NTG+NTGPaired t Test
Ktrans (95% CI) (min−1)Ktrans (95% CI) (min−1)log(Ktrans)
38570.4 (0.2–0.9)1.0 (0.4–2.3)P = .0003b
38640.4 (0.2–0.9)0.5 (0.2–1.3)P = .25
38660.7 (0.3–1.8)1.7 (0.9–3.1)P = .002b
38680.6 (0.2–1.5)1.8 (1.1–2.8)P = .02b
38730.8 (0.4–1.7)1.7 (0.9–3.0)P = .003b
38810.7 (0.3–1.7)0.7 (0.2–1.7)P = .72
38840.5 (0.2–1.1)0.6 (0.3–1.4)P = .02b
38930.6 (0.3–1.3)1.8 (1.0–3.3)P = .002b
  • a The t test demonstrated significantly higher values after intravenous infusion of nitroglycerine in 6 of 8 animals. The columns −NTG and +NTG represent back-transformed values with and without nitroglycerine, respectively.

  • b Significant.