Characteristic | True Progression (n = 24) | Pseudoprogression (n = 18) | P Value |
---|---|---|---|
Age (yr) | 60.50 ± 11.58 | 48.22 ± 12.54 | .002 |
Sex | .347 | ||
Male | 17 | 10 | |
Female | 7 | 8 | |
Karnofsky performance score | .371 | ||
<70 | 4 | 1 | |
≥70 | 20 | 17 | |
Surgery | .623 | ||
Biopsy | 3 | 1 | |
Resection | 21 | 17 | |
Radiation dose (Gy) | 55.52 ± 8.17 | 57.83 ± 7.52 | .376 |
Methylated MGMT promotera | 1.000 | ||
Negative | 6 | 5 | |
Positive | 15 | 13 |
Note:—MGMT indicates O6-methylguanine DNA methyltransferase.
↵a The promoter methylation status of MGMT, which was investigated by using the methylation-specific polymerase chain reaction technique, was documented whenever available.