Characteristics of patients with and without reversion of collateralsa
| Reversion of Collaterals | P Value | ||
|---|---|---|---|
| Yes (n = 25) | No (n = 23) | ||
| Age (median) (IQR) | 78 (71–81) | 79 (68–86) | .52 |
| Male sex (No.) (%) | 13 (52) | 13 (57) | .78 |
| mRS 0–1 before stroke (No.) (%) | 25 (100) | 22 (96) | .48 |
| Cardiovascular risk factors (No.) (%) | |||
| Hypertension | 15 (60) | 13 (57) | 1 |
| Diabetes mellitus | 7 (28) | 3 (13) | .29 |
| Hyperlipidemia | 4 (16) | 7 (30) | .31 |
| Atrial fibrillation | 21 (84) | 13 (57) | .057 |
| Congestive heart failure | 5 (20) | 4 (17) | 1 |
| Previous stroke | 6 (24) | 6 (26) | 1 |
| Smoking | 9 (36) | 9 (41) | .77 |
| Past medication at stroke onset (No.) (%) | |||
| Antiplatelet therapy | 7 (28) | 8 (35) | .76 |
| Anticoagulant therapy | 5 (20) | 4 (17) | 1 |
| Antihypertensive therapy | 13 (52) | 10 (44) | .58 |
| Statin therapy | 2 (8) | 4 (17) | .41 |
| Stroke etiology (No.) (%) | |||
| Cardioembolism | 19 (76) | 11 (48) | .07 |
| Atherosclerosis | 4 (16) | 8 (35) | .19 |
| Other or undetermined | 2 (8) | 4 (17) | .41 |
| Severity of stroke at arrival (median) (IQR) | |||
| Initial GCS | 13 (11–14) | 12 (10–14) | .62 |
| Initial DWI volume (mL) | 21.6 (13.8–42.5) | 22.9 (10.6–41.1) | .63 |
| DWI ASPECTS at arrival | 8 (7–9) | 8 (6–8) | .72 |
| Initial NIHSS score | 17 (14–24) | 16 (11–21) | .35 |
| Duration between 2 MRI scans (days) | 7 (5–9) | 6 (3–8) | .2 |
| Neurologic and radiologic outcome after rtPA (median) (IQR) | |||
| 24-hr NIHSS | 7 (2–12) | 11 (6–17) | .022b |
| 7-day NIHSS | 4 (1–8) | 8 (3–14) | .008c |
| Hemorrhagic transformation | 6 (24) | 10 (43) | .22 |
| Successful recanalization | 23 (92) | 8 (35) | <.001d |
| Follow-up CT ASPECTS | 8 (6.5–9) | 6 (4–8) | .017b |
| M1 to M6 area in ASPECTS | 5 (4–6) | 3 (2–6) | .021b |
| C, I, L, IC area in ASPECTS | 3 (2.5–4) | 3 (2–3) | .12 |
| mRS 0–1 at 3 mo (No.) (%) | 16 (64) | 8 (35) | .043b |
Note:—GCS indicates Glasgow Coma Scale; C, caudate nucleus; I, insular cortex; L, lenticular nucleus; IL, internal capsule.
↵a For continuous variables, the median and P values (Mann-Whitney U test) are shown. The resulting proportions and the P values (Fisher exact test with Yates correction, when appropriate) are shown.
↵b P < .05.
↵c P < .01.
↵d P < .001 was considered significant.