Demographic, transplant, and Loes characteristics in higher risk patients with cALD (Loes ≥10) analyzed for neurologic function change by pretransplantation gadolinium intensity score
| GIS 0/1 (n = 7) | GIS 2/3 (n = 18) | Difference (95% CI) | |
|---|---|---|---|
| Age at HSCT (yr) | |||
| Mean | 10.1 | 9.0 | 1.2 (−1.9–4.2) |
| IQR | 8.1–13.3 | 6.8–10.0 | |
| Pre-HSCT Loes | |||
| Mean | 12.6 | 14.0 | −1.5 (−3.3–0.4) |
| IQR | 11–14 | 11–16 | |
| Donor chimerism (%)a | |||
| Mean | 98.7 | 97.1 | 1.6 (−2.1–5.3) |
| IQR | 100–100 | 92–100 |
Note:—IQR indicates interquartile range.
↵a Donor chimerism reflects the percentage of donor hematopoietic engraftment at the most recent follow-up.