Table 1:

Clinical and imaging characteristicsa

CharacteristicsAll Patients (N = 137)Prominent Space-Occupying Edema (n = 51)No Prominent Space-Occupying Edema (n = 86)P Value
Clinical parameters
    Age (yr) (median) (IQR)66 (53–73)63 (52–72)67 (54–73).31
    Female sex (No.) (%)48 (35)19 (37)29 (34).68
    Prior stroke (No.) (%)20 (15)10 (20)10 (12).18
    Atrial fibrillation (No.) (%)16 (12)8 (16)8 (9).27
    NIHSS (median) (IQR)15 (12–19)18 (13–21)14 (11–18).01b
    IV-rtPA (No.) (%)94 (69)32 (63)62 (72).25
    Intra-arterial treatment (No.) (%)29 (21)11 (22)18 (21).93
Imaging parameters
    Time to admission scan (min) (median) (IQR)100 (64–152)106 (70–240)91 (63–135).11
    NCCT
        Early CT signs of infarction, ASPECTS, (median) (IQR)8 (6–10)7 (4–9)9 (7–10).0001b
    CTP
        CBV deficit, ASPECTS (mean) (SD)4.30 (2.57)3.31 (2.32)4.89 (2.54).001b
        MTT deficit, ASPECTS (median) (IQR)1 (0–3)1 (0–3)2 (0–3).11
        CBV deficit in lentiform nucleus (No.) (%)72 (53)32 (63)40 (47).15
        CBV deficit in caudate nucleus or ACA territory (No.) (%)54 (39)28 (55)26 (30).004b
        Permeability ratio (median) (IQR)c1.36 (1.13–1.88)1.66 (1.24–2.60)1.30 (1.09–1.54).002b
    CTA
        Clot burden score ≤6 (No.) (%)99 (73)44 (86)55 (65).006b
        Thrombus location ICA/M1 proximal (No.) (%)63 (48)33 (67)30 (36).001b
        Poor collateral score (No.) (%)62 (46)34 (68)28 (33).0001b
    Follow-up CTP and CTA
        No recanalizationc26 (33)6 (32)20 (33).89
        No reperfusionc45 (62)16 (76)29 (56).10

  • Note:—IQR indicates interquartile range.

  • ↵a χ2 was used to compare categoric variables, and a t test or Mann-Whitney U test, continuous variables.

  • ↵b All P < .05.

  • ↵c The analysis of permeability ratio, recanalization, and reperfusion is a subanalysis on 101, 79, and 73 cases, respectively.