Table 4:

Brain MR imaging findings of male patients with IVS4 +919G>A and healthy controls

Late-Onset Fabry DiseaseHealthy ControlP Valuea
No.2020
Mean age (SD) (years)59.7 (7.5)58.5 (6.7).547
Infarction6 (30%)0 (0%).010
Area of infarction (anterior circulation/posterior circulation/both)1/1/40/0/0.070
Hemorrhage/microbleeds0 (0%)0 (0%)1.000
White matter scoresb13/5/1/114/5/1/0.792
Pulvinar sign7 (35%)0 (0%).004
Chiari I malformation0 (0%)0 (0%)1.000
Vascular stenosisc1 (5%)2 (10%).513
Mean diameter of BA (SD) (mm)2.91 (0.60)2.43 (0.72).041
Laterality of BAb11/8/1/05/14/1/0.143
Height of BA bifurcationb4/8/87/10/3.191

  • ↵a P, unadjusted.

  • ↵b Scale of 0/1/2/3.

  • ↵c Presence of focal stenosis of all intracranial arteries.