Table 2:

Hypothesized alterations in myelin and iron content in MS lesions associated with commonly observed R2*/QSM lesion contrast patterns

R2* IntensityQSM IntensityAlteration in Myelin ContentAlteration in Iron Content
HypoHyper↓↔
HypoIso↓↓
IsoHyper↓↑

  • Note:—Hypo indicates hypointensity; Hyper, hyperintensity; Iso, isointensity; ↑, increase; ↓, decrease; ↔, little-to-no change.