General characteristicsa
| Characteristics (n = 181) | |
|---|---|
| Age (yr) | 77 (2) |
| Female | 96 (53%) |
| MMSE | 29 (28–30) |
| BMI (kg/m2) | 26 (24–28) |
| History of stroke or TIA | 19 (11%) |
| History of cardiovascular disease | 41 (23%) |
| Diabetes mellitus | 20 (11%) |
| Smoking status | |
| Never | 82 (45%) |
| Former | 88 (49%) |
| Current | 11 (6%) |
| Antihypertensive drug use | 108 (60%) |
| World Health Organization hypertension grade: | |
| Normotension | 47 (26%) |
| Grade I hypertension | 73 (41%) |
| Grade II hypertension | 38 (21%) |
| Grade III hypertension | 20 (11%) |
| Systolic blood pressure (mm Hg) | 148 (138–165) |
| Diastolic blood pressure (mm Hg) | 81 (74–90) |
| Brain parenchymal fraction | 0.61 (0.025) |
| WMH volume (mL) | 6.5 (3.6–11.2) |
Note:—MMSE indicates Mini-Mental State Examination; BMI, body mass index.
↵a Reported are means and SDs, numbers and valid percentages, or medians with interquartile range. Cardiovascular disease comprises peripheral arterial disease, angina pectoris, and myocardial infarction. Brain parenchymal fraction = (total cerebral volume)/total intracranial volume.