Patient | Sex/Age (yr) | Symptoms | Lesion Location | Lesion Size (cm) | Durationb (mo) | IDH1 Mutation | ||
---|---|---|---|---|---|---|---|---|
Type II | Type III | Classic GB | ||||||
1 | M/55 | Focal seizure | Right insula and temporal cortex | 5 | 6 | NA | 11 | − |
2 | M/57 | Focal seizure | Left parietal cortex | 2.2 | NA | NA | 7 | + |
3 | M/60 | Focal seizure | Right insula and frontal operculum | 3 | NA | NA | 8 | − |
Note:—NA indicates not available; +, positive; −, negative.
↵a The lesions refer to the FLAIR/T2-weighted hyperintensities predominantly involving cortical GM. Their perpendicular diameters were <1 cm and therefore not measured.
↵b The duration is the time interval between the first and follow-up MR imaging studies showing type II lesions, type III lesions, or classic GB, respectively. NA indicates that the particular lesion type was not detected during the course of follow-up.