Table 1:

Clinical characteristics of patients who presented with type I lesionsa

PatientSex/Age (yr)SymptomsLesion LocationLesion Size (cm)Durationb (mo)IDH1 Mutation
Type IIType IIIClassic GB
1M/55Focal seizureRight insula and temporal cortex56NA11
2M/57Focal seizureLeft parietal cortex2.2NANA7+
3M/60Focal seizureRight insula and frontal operculum3NANA8
  • Note:—NA indicates not available; +, positive; −, negative.

  • a The lesions refer to the FLAIR/T2-weighted hyperintensities predominantly involving cortical GM. Their perpendicular diameters were <1 cm and therefore not measured.

  • b The duration is the time interval between the first and follow-up MR imaging studies showing type II lesions, type III lesions, or classic GB, respectively. NA indicates that the particular lesion type was not detected during the course of follow-up.