Univariate analysis of baseline characteristics, procedural variables, and outcomes associated with 90-day mRS > 2a
| All Patients (n = 256b) | 90-Day mRS 0–2 (n = 152) | 90-Day mRS >2 (n = 104) | P Value | |
|---|---|---|---|---|
| Demographics | ||||
| Age (yr) | 65.2 ± 15.4 | 61.5 ± 15.1 | 70.7 ± 14.1 | <.01c |
| Male sex | 123 (48%) | 76 (50%) | 47 (46%) | .49 |
| Current smoker | 48 (19%) | 30 (20%) | 18 (17%) | .61 |
| Hypertension | 179 (70%) | 102 (67%) | 77 (74%) | .23 |
| Diabetes mellitus | 58 (23%) | 35 (23%) | 23 (22%) | .86 |
| Dyslipidemia | 92 (36%) | 55 (36%) | 37 (36%) | .92 |
| Atrial fibrillation | 95 (37%) | 49 (32%) | 46 (44%) | .06c |
| Stroke features | ||||
| Baseline NIHSS | 17 (13–22) | 15 (11–19) | 20 (17–24) | <.01c |
| ASPECTS | 8 (7–9) | 9 (7–9) | 7 (6–9) | <.01c |
| Occlusion site | ||||
| ICA terminus | 46 (18%) | 18 (12%) | 28 (27%) | <.01c |
| MCA M1 | 158 (72%) | 98 (64%) | 60 (58%) | .27 |
| Last healthy to puncture (min) | 295 (219–457) | 281 (208–460) | 305 (236–449) | .34 |
| IV tPA given | 113 (44%) | 71 (47%) | 42 (41%) | .35 |
| Intraprocedural management | ||||
| Stent retriever | 189 (74%) | 115 (76%) | 74 (72%) | .44 |
| Procedure time (min) | 62 (41–88) | 60 (41–81) | 66 (40–91) | .23 |
| Vasopressor use | 134 (52%) | 75 (49%) | 59 (57%) | .24 |
| Outcomes | ||||
| Parenchymal hemorrhage | 19 (7%) | 4 (3%) | 15 (14%) | <.01c |
| Final infarct volume (cm3) | 20.5 (7.3–60.0) | 13.4 (5.4–35.6) | 30.6 (17.4–111) | <.01 |
| 90-day mRS | 2 (1–4) | |||
| Mortality | 31 (12%) | 31 (30%) |
Note:—M1 indicates the sphenoidal segment of middle cerebral artery.
↵a Results are shown as mean ± SD, median (interquartile range), or number (percentage).
↵b Not all patients had data available for ASPECTS (n = 243), minutes from last known healthy to groin puncture (n = 211), or final infarct volume (n = 217).
↵c Variables with P < .1 added to the multivariate models.