Table 2:

Lifetime brain cancer risksa

Age at Treatment (yr)SexLife Expectancy (mRS Score)Lifetime Brain Cancer Risk (per 100,000 Individuals) (Mean) (95% CI)
70MNormal (0–2)8.14 (1.52–23.82)
70MReduced (3–5)2.33 (0.44–6.82)
70FNormal (0–2)2.47 (0.52–6.84)
70FReduced (3–5)0.66 (0.14–1.83)
50MNormal (0–2)27.35 (5.25–80.16)b
50MReduced (3–5)5.26 (1.01–15.40)
50FNormal (0–2)7.32 (1.55–20.36)
50FReduced (3–5)1.39 (0.29–3.85)
  • a Risks were calculated using NCI methodology (https://irep.nci.nih.gov/radrat/), adjusted for life expectancy.15 The average dose for a CT+CTA+CTP examination was estimated from published literature.16

  • b To assume a conservative approach, we used the highest modeled risk (50-year-old male patient with normal life expectancy) for our base case scenario.