Associations between flow characteristics and composition of the sIA walla
Hemodynamic Variable | Wall Type | |||
---|---|---|---|---|
A | B | C | P Values | |
ICI | 2.24 (1.92–2.56) | 0.62 (0.11–2.91) | 0.36 (0.22–1.67) | pAB = .119, pAC = .04,b pBC = .334 |
Q | 1.71 (1.22–2.19) | 0.67 (0.52–2.32) | 0.52 (0.31–0.95) | pAB = .081, pAC = .041,b pBC = .291 |
Corelen | 5.56 (4.31–6.81) | 1.48 (0.00–3.11) | 0.46 (0.03–4.80) | pAB = .021,b pAC = .088, pBC = .476 |
Podent | 0.55 (0.37–0.74) | 0.24 (0.13–0.54) | 0.19 (0.13–0.44) | pAB = .034,b pAC = .088, pBC = .334 |
OSImax | 0.47 (0.46–0.49) | 0.36 (0.26–0.46) | 0.28 (0.10–0.44) | pAB = .034,b pAC = .041,b pBC = .213 |
OSI | 0.044 (0.03–0.05) | 0.02 (0.01–0.03) | 0.01 (0.00–0.03) | pAB = .021,b pAC = .041,b pBC = .427 |
Note:—ICI indicates inflow concentration index; Q, inflow rate into the aneurysm; corelen, vortex core line length, a measure of flow complexity; podent, proper orthogonal decomposition entropy, a measure of flow instability.
↵a Median and range are given for the hemodynamic variables in each wall type group, and corresponding P values for comparisons between groups are given. pAB = P value (A vs B), pAC = P value (A vs C), pBC = P value (B vs C). Group A is defined by an intact-looking wall with linearly organized smooth muscle cells and intact endothelium; group B, by smooth muscle cell hyperplasia; and group C, by loss of smooth muscle cells and endothelial cells complemented by degeneration of the extracellular matrix and luminal thrombosis.
↵b Significant.