Patient characteristics and univariate comparison with the patients excluded for radiologic reasonsa
| Study Population (N = 2209) | Excluded Patients (n = 443) | P Value | |||
|---|---|---|---|---|---|
| No. | % or IQR | No. | % or IQR | ||
| Female sex (%) | 929 | 42.1 | 216 | 48.8 | <.01 |
| Age (yr) (IQR) | 72 | 21 | 77 | 24 | <.01 |
| Risk factors | |||||
| Hypertension (%) | 1268 | 66.9 | 318 | 71.8 | .02 |
| Heart valves (%) | 61 | 3.2 | 11 | 2.5 | .51 |
| Coronary artery disease (%) | 295 | 15.5 | 80 | 18.1 | .20 |
| Dyslipidemia (%) | 1325 | 69.5 | 270 | 60.9 | <.01 |
| Diabetes (%) | 331 | 17.4 | 82 | 18.5 | .34 |
| Atrial fibrillation (%) | 480 | 25.2 | 141 | 31.8 | <.01 |
| Low ejection fraction (%) | 91 | 4.7 | 24 | 5.4 | .60 |
| Smoking (%) | 807 | 42.3 | 160 | 36.1 | .06 |
| Stroke mechanism | |||||
| Atherosclerosis (%) | 304 | 13.8 | 99 | 22.3 | .05 |
| Undetermined (%) | 553 | 25 | 92 | 20.8 | .06 |
| Cardiac (%) | 641 | 29 | 145 | 32.7 | .12 |
| Lacunar/microangiopathic (%) | 269 | 12.2 | 62 | 14.0 | .19 |
| Dissections (%) | 107 | 4.8 | 14 | 3.2 | .07 |
| PFO/other determined/rare (%) | 159 | 7.2 | 40 | 9.0 | .07 |
| Multiple/coexisting (%) | 118 | 5.3 | 21 | 4.7 | .48 |
| NIHSS admission (IQR) | 7 | 12 | 5 | 9 | <.01 |
| Onset-to-CT delay (IQR) (min) | 275 | 565 | 420 | 667 | <.01 |
| Door-to-CT delay (IQR) (min) | 183 | 469 | 380 | 771 | <.01 |
Note:—IQR indicates interquartile range; PFO, patent foramen ovale.
↵a Values are expressed as medians and IQR for continuous variables or absolute counts and percentage for categoric variables unless otherwise stated.