Correlation with clinical measuresa
| Region and MRI Metrics | mJOA Score (n = 98) | UE Motor Score (n = 196) | UE Sensory Score (n = 196) |
|---|---|---|---|
| Rostral | |||
| CSA | 0.44 (6 × 10−6) | – | – |
| FA | 0.37 (2 × 10−4) | 0.20 (0.006) | 0.26 (3 × 10−4) |
| MTR | 0.35 (5 × 10−4) | 0.22 (0.002) | 0.11 (0.13) |
| T2*WI WM/GM | −0.52 (5 × 10−8)b | −0.45 (7 × 10−11)b | −0.49 (4 × 10−13)b |
| MCL/C4–5 | |||
| CSA | 0.66 (2 × 10−13)b | – | – |
| FA | 0.54 (2 × 10−8) | 0.36 (5 × 10−7)b | 0.40 (1 × 10−8) |
| MTR | 0.43 (1 × 10−5) | 0.14 (0.04) | 0.05 (0.48) |
| T2*WI WM/GM | −0.59 (7 × 10−10) | −0.33 (3 × 10−6) | −0.43 (8 × 10−10)b |
| Caudal | |||
| CSA | 0.27 (0.007) | – | – |
| FA | 0.35 (0.001) | 0.09 (0.20) | 0.05 (0.49) |
| MTR | 0.02 (0.83) | 0.12 (0.11) | 0.05 (0.51) |
| T2*WI WM/GM | −0.36 (3 × 10−4)b | −0.17 (0.01)b | −0.25 (6 × 10−4)b |
↵a mJOA is analyzed against FA, MTR, and T2*WI WM/GM extracted from total WM and SC CSA. UE motor score and UE sensory score are analyzed with respect to non-CSA metrics extracted from the ipsilateral, lateral corticospinal tract and fasciculus cuneatus, respectively. Pearson coefficients are shown with P values in parentheses.
↵b Strongest correlations with clinical measures for each region.