Angiographic outcomes and treatment-related complications

VariablesRaw NumbersaNo. of Articles95% CII2P Value
MCA aneurysm occlusion after flow diversion
    Overall rate of complete/near-complete occlusion137/171 = 78.7%1067.8–89.776.24<.001
Factors related to aneurysm occlusion
    Mean age (yr).262
        Complete/near-complete occlusion53.6 yr447.3–59.875%
        Incomplete occlusion61.3 yr48.9–73.595%
Mean size.614
    Complete/near-complete occlusion7 mm63.6–10.383.6%
    Incomplete occlusion5.5 mm0.8–10.199%
Complete/near-complete occlusion.38
    Retreatment64%533.9–93.475.2%
        vsvs
        First treatment73%63–83.50%
Complete/near-complete occlusion.307
    Prebifurcation (M1–early cortical branches)88.1%1179.6–96.70%
        vsvs
        Bifurcation aneurysms77.7%64.5–89.574.92%
Complications related to treatment and outcome
    Overall rate of treatment-related complications46/213 = 20.7%1114–27.534.03%.126
    Transient or asymptomatic11.3%7.6–16.2
        vsvs116.8–15.2
        Permanent10.3%
    Type of complications
        Ischemic/thromboembolic16.3%1110.1–22.636.65%.106
        Hemorrhagic2%0.2–3.90%.958
        Iatrogenic (dissection/perforation)1.8%0%–1.3.5%0%.973
        Perianeurysmal inflammation2.6%0.5–4.70%.997
    Complications related to discontinuation of antiplatelet therapy4/46 = 8.7%112.9–20.8
    Aneurysm rupture after treatment1/214 = 0.47%120.1–2.8
    Overall rate of good outcome125/135 = 92.7%786.4–99.142.08%.11
    Mortality rate4/213 = 2%110.2–3.9%0%.929
  • Note:— vs indicates versus.

  • a Results of meta-analysis.