Angiographic outcomes for unruptured and ruptured very large/giant intracranial aneurysms—comparison between reconstructive and deconstructive treatments
| Variables | Unruptured Group (Results of Meta-Analysis) | No. of Articles | P Value | Ruptured Group (Results of Meta-Analysis) | No. of Articles | P Value |
|---|---|---|---|---|---|---|
| Angiographic outcomes | ||||||
| Long-term aneurysm occlusion (complete/near-complete) | 122/175 = 71% | 14 | 23/31 = 72% | 5 | ||
| Reconstructive | (60–81) (I2 = 69%) | (57–87) (I2 = 0%) | ||||
| vs | .003a | .5 | ||||
| Deconstructive | 147/158 = 93% | 13/15 = 80% | 4 | |||
| (89–98) (I2 = 4%) | 8 | (60–97) (I2 = 42%) | ||||
| Recanalization after reconstructive treatment | 45/110 = 40% | 9 | 15/31 = 47% | 4 | ||
| (13–60) (I2 = 95%) | (30–64) (I2 = 0%) | |||||
| vs | .001a | .1 | ||||
| Recanalization after deconstructive treatment | 3/66 = 5% | 1/8 = 22% | ||||
| (1–10) (I2 = 0%) | 6 | (7–52) (I2 = 49%) | 3 | |||
| Time between treatment and recanalization | ||||||
| Reconstructive | Median, 5 mo; mean, 8.7 mo; IQR, 4–13.5 | |||||
| vs | vs | |||||
| Deconstructive | Median 6 mo; mean 13 mo; IQR, 5–21 | |||||
| Retreatment after reconstructive treatment | 34/105 = 32% | 8 | 14/29 = 48% | 3 | ||
| (10–55) (I2 = 90%) | (30–66) (I2 = 0%) | |||||
| vs | .001a | .007a | ||||
| Retreatment after deconstructive treatment | 1/66 = 4% | 1/8 = 22% | ||||
| (1–8) (I2 = 0%) | 6 | (7–52) (I2 = 49%) | 3 | |||
| Early aneurysm rupture after reconstructive treatment | 8/165 = 5% | 14 | 3/37 = 8% | 6 | ||
| vs | (1.7–8) (I2 = 0%) | .08 | (2–22) (I2 = 5%) | .2 | ||
| Early aneurysm rupture after deconstructive treatment | 0/86 | 8 | 0/36 | 5 | ||
| Late aneurysm rupture after reconstructive treatment | 3/148 = 3% | 12 | 0/36 | 5 | ||
| vs | (0.6–6.2) (I2 = 0%) | .4 | .4 | |||
| Late aneurysm rupture after deconstructive treatment | 0/86 | 8 | 0/10 | 4 | ||
Note:—vs indicates versus; IQR, interquartile range.
↵a Significant.