Table 1:

Demographic and clinical characteristicsa

Controls n = 15PSP n = 24CBD n = 9MSA n = 19PD n = 18P Value
Demographic data
    Sex (M/F)8:713:114:514:510:8.454b
    Age (yr)62.6 (9.0)63.2 (6.8)67.9 (5.6)64.2 (7.1)64.4 (9.3).433c
    Disease duration (yr)NA3.3 (1.8)3.3 (1.8)3.1 (2.1)10.6 (6.1)<.001c
Clinical data
    UPDRS IIINA21.3 (9.8)25.2 (7.1)19.6 (19.1)32.3 (11.5).875c
    UPDRSbradNA6.1 (4.7)12.5 (3.6)7.7 (9.3)14.5 (8.4).134c
    UPDRSrigNA4.1 (3.0)7.2 (4.4)3.9 (5.6)9.2 (6.5).266c
White matter lesion burden assessment
    Fazekas PVH score0.38 (0.65)0.71 (0.75)0.70 (0.48)0.37 (0.50)0.47 (0.62).321c
    Fazekas DWMH score0.77 (0.73)0.54 (0.66)0.40 (0.52)0.53 (061)0.53 (0.51).684c
  • Note:—DWMH indicates deep white matter hyperintensity; UPDRS, Unified Parkinson Disease Rating Scale; UPDRSbrad, bradykinesia subscore of UPDRS; UPDRSrig, rigidity subscore of UPDRS; PVH, periventricular; NA, not applicable.

  • a Data are presented as mean (SD).

  • b χ2 test.

  • c ANOVA.