Table 1:

Quantitative measurements in the SN^{^a}

Side	PD	HV
3T NM ROI
Volume
L	184.41 ± 68.84	261.45 ± 47.68^{^b}
R	176.91 ± 62.89	258.89 ± 46.62^{^b}
Mean LR	180.66 ± 63.63	260.17 ± 42.87^{^b}
Signal
L	106.74 ± 2.64	110.21 ± 2.55^{^b}
R	106.61 ± 3.32	110.46 ± 2.82^{^b}
Mean LR	110.56 ± 2.62	110.33 ± 2.40^{^b}
FA
L	0.32 ± 0.04	0.34 ± 0.04^{^c}
R	0.31 ± 0.04	0.33 ± 0.04
Mean LR	0.31 ± 0.03	0.33 ± 0.04^{^c}
AD
L	0.68 ± 0.09	0.59 ± 0.10^{^d}
R	0.70 ± 0.08	0.62 ± 0.10^{^c}
Mean LR	0.69 ± 0.08	0.60 ± 0.10^{^c}
RD
L	0.44 ± 0.06	0.38 ± 0.07^{^d}
R	0.46 ± 0.06	0.40 ± 0.07^{^c}
Mean LR	0.45 ± 0.06	0.39 ± 0.07^{^c}
MD
L	0.52 ± 0.07	0.45 ± 0.08^{^d}
R	0.54 ± 0.06	0.48 ± 0.08^{^c}
Mean LR	0.53 ± 0.11	0.46 ± 0.08^{^c}
R2*
L	35.91 ± 4.95	36.66 ± 2.84
R	36.10 ± 6.64	36.54 ± 2.80
Mean LR	35.65 ± 6.46	36.60 ± 2.64
3T T2 ROI
FA
L	0.39 ± 0.06	0.42 ± 0.06
R	0.37 ± 0.06	0.40 ± 0.05
Mean LR	0.38 ± 0.06	0.40 ± 0.05
AD
L	0.50 ± 0.09	0.45 ± 0.10
R	0.53 ± 0.10	0.49 ± 0.11
Mean LR	0.52 ± 0.09	0.47 ± 0.10
RD
L	0.30 ± 0.06	0.26 ± 0.10^{^c}
R	0.33 ± 0.06	0.29 ± 0.06^{^c}
Mean LR	0.32 ± 0.06	0.28 ± 0.0^{^c}
MD
L	0.37 ± 0.07	0.32 ± 0.07^{^c}
R	0.40 ± 0.07	0.35 ± 0.08^{^c}
Mean LR	0.38 ± 0.07	0.34 ± 0.08^{^c}
R2*
L	28.47 ± 4.17	30.21 ± 3.23
R	28.91 ± 3.98	29.93 ± 2.87
Mean LR	28.69 ± 3.97	30.07 ± 2.88
7T T2*WI ROI
T2WI volume
L	459.75 ± 120.74	541.14 ± 118.80^{^c}
R	468.11 ± 130.00	523.01 ± 121.85^{^c}
Mean LR	463.93 ± 122.83	532.07 ± 118.33^{^c}

Note:—L indicates left; R, right; LR, average of left and right.
↵a Quantitative measurements in the substantia nigra (mean and SD) are presented.
↵b Significant differences between patients with PD and HVs are indicated using P < .001.
↵c Significant differences between patients with PD and HVs are indicated using P < .05.
↵d Significant differences between patients with PD and HVs are indicated using P < .005.