Table 4:

Pre- and postinitiation of chronic transfusion therapy ASL perfusion changesa

PtPretransfusionPosttransfusionP Value
MCA (R)MCA (L)ACA (R)ACA (L)PCA (R)PCA (L)AvgMCA (R)MCA (L)ACA (R)ACA (L)PCA (R)PCA (L)Avg
196NA78NA93NA8995NA94NA87NA92.69
279716465627369NA87NA84NA8084.06
3103911029811110710275787676737576<.001b
4NA89NA80NA8083NA75NA82NA7678.37
590968193828888939695101919395.02c
6841028810078839079968186787683.02b
79893889092889281847485748381.005b
87068706565646774796471606068.74
97070646663716769747785738087.02c
T8678798281828181848080777880.47
  • Note:—Pt indicates patient; R, right; L, left; Avg, average/mean whole-brain CBF; NA, not applicable/excluded; T, mean of each arterial territory.

  • a Arterial territory–specific and mean whole-brain CBF values (in milliliters/100 g of tissue/min) from 9 patients with transfusion prior to (left columns) and at the first scan after (right columns) transfusion initiation. In the interest in space and simplicity, CBF values were rounded to the nearest whole number for this display.

  • b Significant.

  • c Significant increase in mean whole-brain CBF.