Comparison of MRI-measured optic nerve area between patients' affected and unaffected eyes and healthy eyes of controls and comparison of RNFL thickness between patients' affected and unaffected eyesa
Optic Nerves | |||
---|---|---|---|
Patients' Affected (n = 34) | Patients' Unaffected (n = 18) | Healthy (n = 90) | |
RNFL (μm) | 67.12 ± 13.55 | 94.00 ± 8.66 | NA |
Pp < .001 | |||
Optic nerve area (mm2) | 3.09 ± 1.09 | 5.27 ± 1.39 | 6.27 ± 2.64 |
Pp = .008 | Pc < .001 | ||
Puc = .21 |
Note:—NA indicates not applicable; Pc, comparison between patients' affected optic nerves and control optic nerves; Pp, comparison between patients' affected and unaffected optic nerves; Puc, comparison between patients' unaffected optic nerves and control optic nerves.
↵a Data are mean ± SD unless otherwise indicated. No OCT data were available for the 90 healthy eyes in the control population because these individuals did not have clinical symptoms to warrant OCT measurement.