Comparison of MRI-measured optic nerve area between patients' affected and unaffected eyes and healthy eyes of controls and comparison of RNFL thickness between patients' affected and unaffected eyes^a

	Optic Nerves
	Patients' Affected (n = 34)	Patients' Unaffected (n = 18)	Healthy (n = 90)
RNFL (μm)	67.12 ± 13.55	94.00 ± 8.66	NA
		P_p < .001
Optic nerve area (mm²)	3.09 ± 1.09	5.27 ± 1.39	6.27 ± 2.64
		P_p = .008	P_c < .001
			P_uc = .21

Note:—NA indicates not applicable; P_c, comparison between patients' affected optic nerves and control optic nerves; P_p, comparison between patients' affected and unaffected optic nerves; P_uc, comparison between patients' unaffected optic nerves and control optic nerves.
↵a Data are mean ± SD unless otherwise indicated. No OCT data were available for the 90 healthy eyes in the control population because these individuals did not have clinical symptoms to warrant OCT measurement.