Table 2:

Cortical thickness measurements in the ipsilateral region surrounding focal areas of leptomeningeal contrast enhancement and in the contralateral regiona

Entire Cohort (80 LMCE Foci)Patients with RRMS (55 LMCE Foci)Patients with SPMS (25 LMCE Foci)
DilationsIpsilateralContralateralPct. Diff.P/FDR-PIpsilateralContralateralPct. Diff.P/FDR-PIpsilateralContralateralPct. Diff.P/FDR-P
52.043 (.515)2.149 (.556)−5.06.07/.1872.031 (.534)2.212 (.567)−8.53.005/.04b2.070 (.480)2.000 (.510)3.44.562/.823
102.063 (.437)2.160 (.476)−4.59.016/.1282.099 (.455)2.211 (.501)−5.20.011/.044b1.979 (.387)2.039 (.396)−2.99.493/.823
152.088 (.411)2.153 (.413)−3.07.039/.1562.141 (.414)2.208 (.432)−3.08.055/.1471.964 (.383)2.023 (.339)−2.96.384/.823
202.114 (.286)2.136 (.385)−1.04.409/.5542.167 (.394)2.196 (.395)−1.33.365/.4171.989 (.342)2.000 (.325)−.55.895/.895
252.116 (.362)2.131 (.368)−.71.485/.5542.167 (.376)2.194 (.377)−1.24.306/.4081.996 (.301)1.983 (.306)0.65.749/.856
302.113 (.348)2.131 (.354)−.85.342/.5542.162 (.363)2.195 (.361)−1.51.137/.2741.997 (.284)1.980 (.291)0.85.617/.823
352.115 (.338)2.127 (.342)−.57.483/.5542.165 (.353)2.190 (.347)−1.15.191/.3061.998 (.273)1.977 (.284)1.06.509/.823
402.117 (.327)2.120 (.332)−.14.882/.8822.168 (.341)2.180 (.336)−.55.529/.5291.998 (.261)1.979 (.282)0.95.485/.823
  • Note:—Pct. Diff. indicates percentage difference; FDR, false discovery rate.

  • Ipsilateral and contralateral columns represent mean (standard deviation) cortical thickness measures in millimeters.

  • a Paired t tests comparing the ipsilateral and contralateral regions were used to calculate P values. The Benjamini-Hochberg procedure was used to control the false discovery rate.

  • b Corrected P values < .05.