Table 1:

Patient demographics and clinical and biologic lesion characterization

Age (yr)SexOverall Survival (mo)LocationLMASCL1CKBGermline Mutation
0.15F0.5aPosterior fossa0Negative5.05
0.32F17.0Posterior fossa0Positive6.31Yes
0.39M8.2bPosterior fossa1Positive
0.64M7.0Parietal lobe0Negative5.10
0.67M0.5aPosterior fossa1Positive
0.68M5.1Intraventricular0ND
0.92F0.5aPosterior fossa1PositiveYes
0.95M71.9bPosterior fossa0ND
1.09M13.0Posterior fossa0Negative5.31
1.14M7.0Temporal lobe0Positive6.05Yes
1.15M59.0Posterior fossa0Negative6.31
1.42F9.0Posterior fossa1ND
1.54M32.0Temporal lobe0Positive6.53Yes
1.55M63.2bPosterior fossa0Negative
1.73M13.0Pineal0Positive
1.84F18.0Frontotemporal0Negative5.21
1.96FNATemporal lobe1ND
2.86M18.0Frontotemporal1Positive6.61
7.43F40.0Frontotemporal0Positive6.42
13.72M40.0Intraventricular0Positive5.71
  • Note:—NA indicates patient lost to follow up; LM, leptomeningeal disease present (1) versus absent (0) at presentation; ND, not determined.

  • a Patients who died from surgical/other complications with no MR imaging or clinical evidence of progressive tumor.

  • b Patients who were still alive at the time of the completion of this study.