Location | Neurologic Presentation | Comments |
---|---|---|
PNS | Subacute meningitis24 | Most common presentation in North America24 |
Plexus neuritis or mononeuritis multiplex25 | 5%–10% cases25 | |
Bannwarth syndrome15 | Uncommon in North America15 | |
Cranial nerve | Facial nerve neuritis26,27 | Most commonly involved cranial nerve26 |
CN III and CNV28,29 | Few case reports28,29 | |
CNS | Nonspecific bifrontal white matter T2 hyperintensity15 | 50% of cases with CNS involvement15 |
Encephalitis-rhombencephalitis pattern likely25 | Rare15 | |
Vasculitis15 | Rare15 | |
Spinal cord | Nonspecific areas of T2 prolongation15 | Most common pattern in spinal cord involvement15 |
Ocular | Conjunctivitis and episcleritis, early stages33,34 | Rare33,34 |
Uveitis, orbital myositis, chronic intraocular inflammation33,34 | Rare33,34 | |
Pediatric | Cranial neuritis and meningitis35,36 | Most common pediatric neurologic presentation35,36 |
Peripheral neuritis, myelitis, Bannwarth syndrome37,38 | Rare37,38 | |
Prominent Virchow-Robin spaces37,38 | Less common37,38 |
Note:—CN indicates cranial nerve; PNS, peripheral nervous system.