Outcomes of patients with no-to-minimal (van Swieten score, 0–2) and moderate-to-severe (van Swieten score, 3–4) white matter disease
| Outcome | van Swieten 0–2 (n = 315) | van Swieten 3–4 (n = 74) | Unadjusted OR with 95% CI | P Value | Adjusted OR with 95% CI | P Value |
|---|---|---|---|---|---|---|
| 90-Day mRS 0–2 (%) | 141/295 (45) | 13/70 (18) | 0.25 (0.13–0.46) | <.001 | 0.37 (0.17–0.75) | .008 |
| 90-Day mRS 0–3 (%) | 184/295 (58) | 29/70 (39) | 0.43 (0.25–0.73) | .002 | 0.75 (0.40–1.43) | .38 |
| Shift in the 90-day mRS | NA | NA | 2.86 (1.83–4.52) | <.001 | 3.05 (1.93–4.84) | <.001 |
| Death (%) | 47 (15) | 19 (26) | 1.97 (1.06–3.57) | .029 | 1.14 (0.56–2.26) | .71 |
| Symptomatic ICH (%) | 13 (4) | 4 (5) | 1.33 (0.37–3.88) | .629 | NA | NA |
| mTICI ≥ 2b (%) | 275 (87) | 68 (92) | 1.65 (0.72–4.47) | .27 | NA | NA |
| ENI (%) | 132 (42) | 30 (40) | 0.95 (0.56–1.58) | .83 | NA | NA |
Note:—mTICI indicates modified TICI; ENI, early neurologic improvement; NA, not applicable.